Article
A mutant Stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice.
The Journal of biological chemistry - 19 Mar 2004
Davoodi-Semiromi Abdoreza, Laloraya Malini, Kumar G Pradeep, Purohit Sharad, Jha Rajesh Kumar, She Jin-Xiong
Abstract excerpt
A number of cytokines that finely regulate immune response have been implicated in the pathogenesis or protection of type 1 diabetes and other autoimmune diseases. It is, therefore, of pivotal importance to examine a family of proteins that serve as signal transducers and activators of transcript...
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