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Article

The STAT5b Pathway Defect and Autoimmunity

1 Jan 2012

Abstract excerpt

The signal transducer and activator of transcription (STAT) 5b is a universal transcription factor that plays key biological roles in allergic diseases, immunodeficiencies, autoimmunities, cancers, hematological diseases, growth disorders, and lung diseases. The identification of distinct pathological manifestations of STAT5b deficiency in humans has highlighted the critical role of the STAT5b pathway. Proper...

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PMID: 22912632
DOI: 10.3389/fimmu.2012.00234

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