Article
Lectin reactivities as intermediate biomarkers in premalignant colorectal epithelium.
Journal of cellular biochemistry. Supplement - 1 Jan 1992
Boland C R, Martin M A, Goldstein I J
Abstract excerpt
Normal colonic epithelial cells undergo maturation as they traverse the crypt to the lumenal surface. The binding of lectins to goblet cell mucins and other glycoconjugates changes as the cells migrate and differentiate. Additional stepwise modifications in glycoconjugate expression occur in premalignant and malignant neoplasms that may be detected by lectin binding studies. The lectins Dolichos biflorus...
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