Article
Colonic carcinogenesis along different genetic routes: glycophenotyping of tumor cases separated by microsatellite instability/stability.
Histochemistry and cell biology - 1 Aug 2012
Gebert Johannes, Kloor Matthias, Lee Jennifer, Lohr Michaela, André Sabine, Wagner Rudolf, Kopitz Juergen, Gabius Hans-Joachim
Abstract excerpt
Different genetic routes account for colonic carcinogenesis. However, when analyzing colon cancer specimens, separation into different groups based on genetic alterations is commonly not performed. Thus, we here initiate the comparative phenotyping considering microsatellite instability/stability for clinical specimens. The focus is given to glycan epitopes, expression of which is known to be modulated by...
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