Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lectin–epithelial interactions in the human colon

19 Nov 2008

Abstract excerpt

Similar changes in glycosylation occur in the colonic epithelium in inflammatory conditions such as ulcerative colitis and Crohn's disease and also in colon cancer and precancerous adenomatous polyps. They include reduced length of O-glycans, reduced sulfation, increased sialylation and increased expression of oncofetal carbohydrate antigens, such as sialyl-Tn (sialylalpha2-6GalNAc), and the TF antigen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Glycosylation and Glycoproteins Research
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19021580
DOI: 10.1042/bst0361482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lectin–epithelial interactions in the human colonPMID 19021580Read ↗

High Diversity of Glycosphingolipid Glycans of Colorectal Cancer Cell Lines Reflects the Cellular Differentiation Phenotype.Semantic proximity Read ↗

Arthritis-Associated Inflammation Remodels Colonic O-GlycosylationSemantic proximity Read ↗

Epithelial glycosylation in gut homeostasis and inflammation.Semantic proximity Read ↗

The expression of human FUT1 in HT-29/M3 colon cancer cells instructs the glycosylation of MUC1 and MUC5AC apomucinsSemantic proximity Read ↗

Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype.Semantic proximity Read ↗

C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progressionSemantic proximity Read ↗

Plasma Glycoprotein Profiling for Colorectal Cancer Biomarker Identification by Lectin Glycoarray and Lectin BlotSemantic proximity Read ↗

Probing the role of glycocalyx in host-microbe interactions with systematic modification of the glycomic surfaceSemantic proximity Read ↗

The Role of Sialyl-Tn in CancerSemantic proximity Read ↗

Rho GTPase Rac1: molecular switch within the galectin network and for N-glycan α2,6-sialylation/O-glycan core 1 sialylation in colon cancer in vitro.Semantic proximity Read ↗

Lectin reactivities as intermediate biomarkers in premalignant colorectal epithelium.Semantic proximity Read ↗

The Ulcerative Colitis-Associated Gene NXPE1 Catalyzes Glycan Modifications on Colonic MucinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.