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Article

Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein.

The EMBO journal - 15 Aug 1997

Wu X, Liu H, Xiao H, Conway J A, Hunter E, Kappes J C

Abstract excerpt

The expression and incorporation of retroviral enzymes into virions in the form of Gag/Pol precursor polyproteins is believed to be important for the assembly of infectious viral particles. HIV-1 encodes a 160 kDa Gag/Pol precursor that includes Gag, protease (PR), reverse transcriptase (RT) and integrase (IN). We have developed the use of HIV accessory proteins (Vpr and Vpx) as vehicles to incorporate protein of...

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Identifiers

PMID: 9305652
DOI: 10.1093/emboj/16.16.5113
PMCID: PMC1170145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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