Article
Evolution of human immunodeficiency virus type 1 (HIV-1) resistance mutations in nonnucleoside reverse transcriptase inhibitors (NNRTIs) in HIV-1-infected patients switched to antiretroviral therapy without NNRTIs.
Antimicrobial agents and chemotherapy - 1 Jan 2004
Joly Véronique, Descamps Diane, Peytavin Gilles, Touati Fatiha, Mentre France, Duval Xavier, Delarue Séverine, Yeni Patrick, Brun-Vezinet Françoise
Abstract excerpt
We studied the evolution of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance mutations among 29 human immunodeficiency virus type 1 (HIV-1)-infected patients who experienced virologic failure when receiving an NNRTI-containing regimen (nevirapine, delavirdine, or efavirenz) and subsequently switched to antiretroviral therapy without NNRTIs. Genotypic resistance was determined from plasma samples...
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