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Article

Nonnucleoside Reverse Transcriptase Inhibitor Resistance

1 Mar 2001

Abstract excerpt

Although understanding of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance is less clearly established than that of other classes of antiretroviral drugs, certain facts have been established. The treatment-associated genetic mutation profiles of the available NNRTIs have been mapped, and resistance has been found to develop rapidly after initiation of NNRTI therapy. Despite the chemical diversity...

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PMID: 11264999
DOI: 10.1097/00042560-200103011-00004

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