Article
A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing.
Journal of cellular biochemistry - 1 Dec 1992
Collart D, Romain P L, Huebner K, Pockwinse S, Pilapil S, Cannizzaro L A, Lian J B, Croce C M, Stein J L, Stein G S
Abstract excerpt
A variant human H2B histone gene (GL105), previously shown to encode a 2300 nt replication independent mRNA, has been cloned. We demonstrate this gene expresses alternative mRNAs regulated differentially during the HeLa S3 cell cycle. The H2B-Gl105 gene encodes both a 500 nt cell cycle dependent...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Cell Cycle
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Cloning, Molecular
- DNA
- Genetic Variation
- HeLa Cells
- Histones
