Article
Identification of new TSGA10 transcript variants in human testis with conserved regulatory RNA elements in 5'untranslated region and distinct expression in breast cancer.
Biochimica et biophysica acta. Gene regulatory mechanisms - 1 Sept 2017
Salehipour Pouya, Nematzadeh Mahsa, Mobasheri Maryam Beigom, Afsharpad Mandana, Mansouri Kamran, Modarressi Mohammad Hossein
Abstract excerpt
Testis specific gene antigen 10 (TSGA10) is a cancer testis antigen involved in the process of spermatogenesis. TSGA10 could also play an important role in the inhibition of angiogenesis by preventing nuclear localization of HIF-1α. Although it has been shown that TSGA10 messenger RNA (mRNA) is mainly expressed in testis and some tumors, the transcription pattern and regulatory mechanisms of this gene remain...
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