Article
Short telomeres protect from diet‐induced atherosclerosis in apolipoprotein E‐null mice
19 Dec 2003
Abstract excerpt
By imposing a replicative defect in most somatic cells, gradual telomere attrition during aging is thought to progressively impair cellular function and viability and may contribute to age-related disease. Immune cells play important roles in all phases of atherosclerosis, a multifactorial disease that prevails within the elderly. Because shorter telomeres have been found in circulating blood leukocytes of human...
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