Article
Phenotypic characterization and genealogical tracing in an Afrikaner schizophrenia database.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2004
Karayiorgou Maria, Torrington Marie, Abecasis Gonçalo R, Pretorius Herman, Robertson Brian, Kaliski Sean, Lay Stephen, Sobin Christina, Möller Natalie, Lundy S Laura, Blundell Maude L, Gogos Joseph A, Roos J Louw
Abstract excerpt
Founder populations hold tremendous promise for mapping genes for complex traits, as they offer less genetic and environmental heterogeneity and greater potential for genealogical research. Not all founder populations are equally valuable, however. The Afrikaner population meets several criteria...
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