Article
Genome-wide linkage scan of schizophrenia: a cross-isolate study.
Genomics - 1 Feb 2007
Bulayeva Kazima B, Glatt Stephen J, Bulayev Oleg A, Pavlova Tatiana A, Tsuang Ming T
Abstract excerpt
Genetic isolates are exceptional resources for the detection of susceptibility genes for complex diseases because of the potential reduction in genetic and clinical heterogeneity. However, the outcome of these mapping efforts is dependent upon the demographic history of a given isolated population, with the most significant factors being a constant population size, the number of generations since founding, and...
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