Article
Identification of a common founder couple for 40 South African Afrikaner families with Parkinson's disease.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 12 May 2014
Geldenhuys Gerhard, Glanzmann Brigitte, Lombard Debbie, Boolay Sihaam, Carr Jonathan, Bardien Soraya
Abstract excerpt
BACKGROUND: Afrikaners are a unique ethnic group in South Africa (SA) with well-documented ancestral records spanning a period of over 350 years. They are mainly descended from Dutch, German and French settlers to SA in the 17th and 18th centuries. Today several disorders in this population occur at relatively high frequencies as a result of founder effects.Objective. To determine whether a founder effect for...
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