Article
Genome-wide scan in a large complex pedigree with predominantly male schizophrenics from the island of Kosrae: evidence for linkage to chromosome 2q.
Molecular psychiatry - 1 Jul 2003
Wijsman E M, Rosenthal E A, Hall D, Blundell M L, Sobin C, Heath S C, Williams R, Brownstein M J, Gogos J A, Karayiorgou M
Abstract excerpt
It is widely accepted that founder populations hold promise for mapping loci for complex traits. However, the outcome of these mapping efforts will most likely depend on the individual demographic characteristics and historical circumstances surrounding the founding of a given genetic isolate. The 'ideal' features of a founder population are currently unknown. The Micronesian islandic population of Kosrae, one of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
