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Article

Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice

17 Dec 2003

Abstract excerpt

Utrophin has been studied extensively in recent years in an effort to find a cure for Duchenne muscular dystrophy. In this context, we previously showed that mice expressing enhanced muscle calcineurin activity (CnA*) displayed elevated levels of utrophin around their sarcolemma. In the present study, we therefore crossed CnA* mice with mdx mice to determine the suitability of elevating calcineurin activity in...

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PMID: 14681302
DOI: 10.1093/hmg/ddh037

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Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx micePMID 14681302Read ↗

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