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Article

Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation.

Human molecular genetics - 1 Mar 2015

Al-Rewashdy Hasanen, Ljubicic Vladimir, Lin Wei, Renaud Jean-Marc, Jasmin Bernard J

Abstract excerpt

Duchenne muscular dystrophy (DMD) is caused by the absence of dystrophin along muscle fibers. An attractive therapeutic avenue for DMD consists in the upregulation of utrophin A, a protein with high sequence identity and functional redundancy with dystrophin. Recent work has shown that pharmacological interventions that induce a muscle fiber shift toward a slower, more oxidative phenotype with increased...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25324540
DOI: 10.1093/hmg/ddu535

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation.PMID 25324540Read ↗

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