Article
Nuclear-cytoplasmic interactions affect in utero developmental capacity, phenotype, and cellular metabolism of bovine nuclear transfer fetuses.
Biology of reproduction - 1 Apr 2004
Hiendleder Stefan, Prelle Katja, Brüggerhoff Katja, Reichenbach Horst-Dieter, Wenigerkind Hendrik, Bebbere Daniela, Stojkovic Miodrag, Müller Sigrid, Brem Gottfried, Zakhartchenko Valeri, Wolf Eckhard
Abstract excerpt
We generated a clone of bovine somatic cell nuclear transfer embryos using oocyte pools from defined maternal sources to study nuclear-cytoplasmic interactions. Nucleocytoplasmic hybrids were reconstructed with Bos taurus (Brown Swiss) granulosa cells and oocytes that contained B. taurus A (Simmental), B. taurus B (Simmental), or Bos indicus (Dwarf Zebu) cytoplasm. Another set of embryos was reconstructed with...
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