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Article

'Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells.

Development (Cambridge, England) - 1 Jan 2004

Lassalle Bruno, Bastos Henri, Louis Jean Paul, Riou Lydia, Testart Jacques, Dutrillaux Bernard, Fouchet Pierre, Allemand Isabelle

Abstract excerpt

Stem cells in various somatic tissues (bone marrow, skeletal muscle) can be identified by the 'Side Population' marker based on Hoechst 33342 efflux. We show that mouse testicular cells also display a 'Side Population' that express Bcrp1 mRNA, the ABC transporter responsible for Hoechst efflux in hematopoietic cells. Inhibition of Hoechst efflux by specific BCRP1 inhibitor Ko143 show that germinal 'Side...

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Identifiers

PMID: 14681185
DOI: 10.1242/dev.00918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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'Side Population' cells in adult mouse testis express Bcrp1 gene and are enriched in spermatogonia and germinal stem cells.PMID 14681185Read ↗

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Hoechst 33342 side population identification is a conserved and unified mechanism in urological cancers.Semantic proximity Read ↗

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