Article
Identification and enrichment of spermatogonial stem cells displaying side-population phenotype in immature mouse testis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2004
Falciatori Ilaria, Borsellino Giovanna, Haliassos Nikolaos, Boitani Carla, Corallini Serena, Battistini Luca, Bernardi Giorgio, Stefanini Mario, Vicini Elena
Abstract excerpt
In mammals, spermatogenesis is maintained by spermatogonial stem cells (SSC). In their niche, SSC divide to self-maintain and to produce a transit-amplifying population that eventually enters the meiotic cycle to give rise to spermatozoa. The low number of SSC and the lack of specific markers hinder their isolation and enrichment. Stem cells in several adult tissues can be identified by using their...
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