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Article

Spermatogonial stem cells share some, but not all, phenotypic and functional characteristics with other stem cells.

Proceedings of the National Academy of Sciences of the United States of America - 27 May 2003

Kubota Hiroshi, Avarbock Mary R, Brinster Ralph L

Abstract excerpt

Spermatogonial stem cells (SSCs) are responsible for maintaining spermatogenesis throughout life in the male by continuous production of daughter cells that differentiate into spermatozoa. However, no unique phenotypic markers to identify SSCs have been described. In this study, the SSC surface phenotype was characterized by using flow cytometric cell sorting in conjunction with a transplantation functional assay...

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Identifiers

PMID: 12738887
DOI: 10.1073/pnas.0631767100
PMCID: PMC164473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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