Article
Side population cells and Bcrp1 expression in lung.
American journal of physiology. Lung cellular and molecular physiology - 1 Jul 2003
Summer Ross, Kotton Darrell N, Sun Xi, Ma Bei, Fitzsimmons Kathleen, Fine Alan
Abstract excerpt
Side population (SP) cells are a rare subset of cells found in various tissues that are highly enriched for stem cell activity. SP cells can be isolated by dual-wavelength flow cytometry because of their capacity to efflux Hoechst dye, a process mediated by the ATP-binding cassette transporter breast cancer resistance protein (Bcrp) 1. By performing flow cytometry of enzymedigested mouse lung stained with Hoechst...
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