Article
Combined effects of PPARgamma2 P12A and PPARalpha L162V polymorphisms on glucose and insulin homeostasis: the Québec Family Study.
Journal of human genetics - 1 Jan 2003
Bossé Yohan, Weisnagel S John, Bouchard Claude, Després Jean-Pierre, Pérusse Louis, Vohl Marie-Claude
Abstract excerpt
Peroxisome proliferator-activated receptors gamma2 and alpha are nuclear factors known to be important regulators of lipid and glucose metabolism. Two polymorphisms, namely PPARgamma2 P12A and PPARalpha L162V, were investigated for their individual and interaction effects on glucose and insulin homeostasis. Genotypes were determined in 663 nondiabetic adults participating in the Québec Family Study and who...
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