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Article

Combined effects of the C161T and Pro12Ala PPARγ2 gene variants with insulin resistance on metabolic syndrome: a case-control study of a central Tunisian population.

Journal of molecular neuroscience : MN - 1 Apr 2014

Youssef Sarraj Mohamed, Mohamed Najah, Afef Slimani, Khaldoun Ben Hamda, Fadoua Neffati, Fadhel Najjar Mohamed, Naceur Slimene Mohamed

Abstract excerpt

We investigated the synergism between variants at the PPARγ locus (C161T and Pro12Ala polymorphisms) with insulin resistance on metabolic syndrome (MS). Five hundred twenty-two subjects were investigated for biochemical and anthropometric measurements. The diagnosis of MS was based on the IDF definition (2009). The HOMA 2 was used to determine HOMA-β, HOMA-S, and HOMA-IR from FPG and FPI concentrations. PCR-RFLP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24243083
DOI: 10.1007/s12031-013-0161-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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