Article
Persistence of vaccine-derived polioviruses among immunodeficient persons with vaccine-associated paralytic poliomyelitis.
The Journal of infectious diseases - 15 Dec 2003
Khetsuriani Nino, Prevots D Rebecca, Quick Linda, Elder Melissa E, Pallansch Mark, Kew Olen, Sutter Roland W
Abstract excerpt
To estimate long-term poliovaccine virus persistence among immunodeficient patients with vaccine-associated paralytic poliomyelitis (iVAPP), cases reported in the United States during 1975-1997 were reviewed, with subsequent follow-up and virological testing. Six (16.2%) of 37 subjects excreted poliovaccine viruses for > or =6 months. Partial genomic sequencing of their available poliovirus isolates showed...
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