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Article

Simvastatin stimulates chondrogenic phenotype of intervertebral disc cells partially through BMP-2 pathway.

Spine - 15 Jul 2008

Zhang Huina, Lin Chia-Ying

Abstract excerpt

STUDY DESIGN: In vitro experiment to study the effect of simvastatin on rat intervertebral disc (IVD) cells. OBJECTIVE: To evaluate the time-course effect of simvastatin on the gene expression of bone morphogenetic protein-2 (BMP-2), aggrecan, and collagen type II in rat IVD cells cultured in alg...

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Source

Identifiers

PMID: 18628692
DOI: 10.1097/BRS.0b013e31817c561b

Genes

IVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18628692-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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