Article
[Association of single nucleotide polymorphism in human SCN7A gene with essential hypertension in Chinese].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2003
Zhang Kui-xing, Zhu Ding-liang, He Xin, Zhang Yi, Zhang Hao, Zhao Rong, Lin Jie, Wang Gu-liang, Zhang Kai-yue, Huang Wei
Abstract excerpt
OBJECTIVE: To identify the single nucleotide polymorphisms (SNPs) in the regulatory and coding regions of human SCN7A (sodium channel, voltage-gated, type VII, alpha polypeptide) gene and to investigate the association of some of these SNPs with essential hypertension (EH) in Chinese. METHODS: The promoter region, exons, as well as part of the introns of SCN7A gene were sequenced by a fluorescent labeling...
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