Article
[Relationship between four single nucleotide polymorphisms of epithelial sodium channel alpha subunit gene and essential hypertension of Kazakhs in Xinjiang].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Dec 2009
Xu Hong, Li Nan-fang, Hong Jing, Zhang Li, Zhou Ling, Li Tao, Ou Yang Wei-jin, Cheng Qiu-yan
Abstract excerpt
OBJECTIVE: To explore the relationship between G2139A,G3091A, T663A, and T3593C single nucleotide polymorphisms (SNPs), which are located at the promoter region,13th exon, and 2nd intron of epithelial sodium channel (ENaC) gene, and their haplotypes with essential hypertension (EH) in Kazakhs in Xinjiang. METHODS: A case-control study was conducted including 252 EH patients (EH group) and 254 normotensive...
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