Article
Chromosome condensation defects in barren RNA-interfered Drosophila cells.
Genetics - 1 Nov 2003
Somma Maria Patrizia, Fasulo Barbara, Siriaco Giorgia, Cenci Giovanni
Abstract excerpt
Barren, the Drosophila homolog of XCAP-H, is one of three non-SMC subunits of condensin, a conserved 13S multiprotein complex required for chromosome condensation. Mutations in barren (barr) were originally shown to affect sister-chromatid separation during mitosis 16 of the Drosophila embryo, whereas condensation defects were not detected. In contrast, mutations in yeast homologs of barren result in defective...
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