Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calmodulin point mutations affect Drosophila development and behavior.

Genetics - 1 Dec 1997

Nelson H B, Heiman R G, Bolduc C, Kovalick G E, Whitley P, Stern M, Beckingham K

Abstract excerpt

Calmodulin (CAM) is recognized as a major intermediary in intracellular calcium signaling, but as yet little is known of its role in developmental and behavioral processes. We have generated and studied mutations to the endogenous Cam gene of Drosophila melanogaster that change single amino acids within the protein coding region. One of these mutations produces a striking pupal lethal phenotype involving failure...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Genes, Lethal

Share to Molecular Sequence Data

Share to Phenotype

Share to Point Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 9409836
DOI: 10.1093/genetics/147.4.1783
PMCID: PMC1208346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calmodulin point mutations affect Drosophila development and behavior.PMID 9409836Read ↗

Drosophila calmodulin mutants with specific defects in the musculature or in the nervous system.Semantic proximity Read ↗

Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant.Semantic proximity Read ↗

Movement of calmodulin between cells in the ovary and embryo of drosophila.Semantic proximity Read ↗

Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo.Semantic proximity Read ↗

Mutational analysis of calmodulin in Saccharomyces cerevisiae.Semantic proximity Read ↗

Functional analysis of the single calmodulin gene in the nematode Caenorhabditis elegans by RNA interference and 4-D microscopy.Semantic proximity Read ↗

Diverse essential functions revealed by complementing yeast calmodulin mutants.Semantic proximity Read ↗

Calmodulin Methyltransferase Is Required for Growth, Muscle Strength, Somatosensory Development and Brain FunctionSemantic proximity Read ↗

The calmodulin gene in Neurospora crassa is required for normal vegetative growth, ultraviolet survival, and sexual development.Semantic proximity Read ↗

Drosophila melanogaster as a model system for the study of the function of calcium/calmodulin-dependent protein kinase II in synaptic plasticity.Semantic proximity Read ↗

A temperature-sensitive calmodulin mutant loses viability during mitosis.Semantic proximity Read ↗

Identification of functional connections between calmodulin and the yeast actin cytoskeleton.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.