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Article

Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant.

Genetics - 1 Sept 1998

Arredondo L, Nelson H B, Beckingham K, Stern M

Abstract excerpt

The ubiquitous calcium-binding protein calmodulin (CaM) has been implicated in the development and function of the nervous system in a variety of eukaryotic organisms. We have generated mutations in the single Drosophila Calmodulin (Cam) gene and examined the effects of these mutations on behavior, synaptic transmission at the larval neuromuscular junction, and structure of the larval motor nerve terminal. Flies...

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Identifiers

PMID: 9725845
DOI: 10.1093/genetics/150.1.265
PMCID: PMC1460322

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