Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant.

doi:10.1093/genetics/150.1.265

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Article

Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant.

Genetics - 1 Sept 1998

Arredondo L, Nelson H B, Beckingham K, Stern M

Abstract excerpt

The ubiquitous calcium-binding protein calmodulin (CaM) has been implicated in the development and function of the nervous system in a variety of eukaryotic organisms. We have generated mutations in the single Drosophila Calmodulin (Cam) gene and examined the effects of these mutations on behavio...

Topics

Amino Acid Sequence
Animals
Behavior, Animal
Calmodulin
Drosophila
Larva
Molecular Sequence Data
Mutation
Phenotype
Synapses
Synaptic Transmission

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