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Article

CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects.

Life sciences - 2 Jan 2004

Soga Yoshihiko, Nishimura Fusanori, Ohtsuka Yoko, Araki Hiroaki, Iwamoto Yoshihiro, Naruishi Hisa, Shiomi Nobuyuki, Kobayashi Yoshitomo, Takashiba Shogo, Shimizu Kenji, Gomita Yutaka, Oka Eiji

Abstract excerpt

Previous studies suggested that the onset of phenytoin-induced gingival overgrowth depended on serum phenytoin concentration. Cytochrome P450 2C (CYP2C) plays an important role in phenytoin metabolism. Recently, single nucleotide polymorphisms in the coding region of CYP 2C influencing phenytoin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14659971
DOI: 10.1016/j.lfs.2003.07.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14659971-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects.PMID 14659971Read ↗

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