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Article

Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003

Fisk Harold A, Mattison Christopher P, Winey Mark

Abstract excerpt

The mitotic spindle is essential for the maintenance of genetic stability, and in budding yeast its assembly and function depend on the Mps1 protein kinase. Mps1p is required for centrosome duplication and the spindle checkpoint. Several recent reports demonstrate that vertebrate Mps1 proteins regulate the spindle checkpoint, but reports conflict regarding their role in centrosome duplication. Here we provide...

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Share to Centrosome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14657364
DOI: 10.1073/pnas.2434156100
PMCID: PMC299837

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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