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Article

The different effects of apoptosis and DNA repair on tumorigenesis.

Journal of theoretical biology - 7 Feb 2002

Plotkin Joshua B, Nowak Martin A

Abstract excerpt

Complex multicellular organisms have evolved mechanisms to ensure that individual cells follow their proper developmental and somatic programs. Tumorigenesis, or uncontrolled cellular proliferation, is caused by somatic mutations to those genetic constraints that normally operate within a tissue. Genes involved in DNA repair and apoptosis are particularly instrumental in safeguarding cells against tumorigenesis....

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Identifiers

PMID: 11846602
DOI: 10.1006/jtbi.2001.2471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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