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Article

Adaptation of the myoglobin knockout mouse to hypoxic stress.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Apr 2004

Schlieper Georg, Kim Jie-Hoon, Molojavyi Andrei, Jacoby Christoph, Laussmann Tim, Flögel Ulrich, Gödecke Axel, Schrader Jürgen

Abstract excerpt

Myoglobin knockout (myo-/-) mice were previously reported to show no obvious phenotype but revealed several compensatory mechanisms that include increases in cardiac capillary density, coronary flow, and hemoglobin. The aim of this study was to investigate whether severe hypoxic stress can exhaus...

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Identifiers

PMID: 14656764
DOI: 10.1152/ajpregu.00043.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14656764-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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