Article
GFAP-expressing cells in the postnatal subventricular zone display a unique glial phenotype intermediate between radial glia and astrocytes.
Glia - 1 Oct 2006
Liu Xiuxin, Bolteus Anna J, Balkin Daniel M, Henschel Oliver, Bordey Angélique
Abstract excerpt
Neural stem cells in the adult subventricular zone (SVZ) derive from radial glia and express the astroglial marker glial fibrillary acidic protein (GFAP). Thus, they have been termed astrocytes. However, it remains unknown whether these GFAP-expressing cells express the functional features common to astrocytes. Using immunostaining and patch clamp recordings in acute slices from transgenic mice expressing green...
Topics
- Amino Acid Transport System X-AG
- Animals
- Animals, Newborn
- Astrocytes
- Biomarkers
- Cell Differentiation
- Cell Shape
- Connexins
- Ependyma
- Glial Fibrillary Acidic Protein
- Glutamic Acid
- Green Fluorescent Proteins
- Membrane Potentials