Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif.

doi:10.1046/j.1460-9568.2003.03053.x

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Article

Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif.

The European journal of neuroscience - 1 Dec 2003

Giffard Rona G, Lee Yong-Sun, Ouyang Yi-Bing, Murphy Sherry L, Monyer Hannah

Abstract excerpt

Regulation of pH in the central nervous system is critical to normal brain function and response to pathophysiological conditions. Here we identify two novel variants of the sodium-driven chloride bicarbonate exchanger (NCBE) from brain. The developmental expression pattern seen by in situ hybridization for the 90-bp containing insert (insert A) reveals strong expression in spinal cord and brain beginning in...

Topics

3T3 Cells
Amino Acid Motifs
Ammonium Chloride
Animals
Animals, Newborn
Astrocytes
Bicarbonates
Blotting, Northern
Blotting, Western
Brain
Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Chloride-Bicarbonate Antiporters

Chlorides

Cloning, Molecular

DNA Transposable Elements

Electrophysiology

Embryo, Mammalian

Fluorescent Antibody Technique

Source

Open in PubMed

Identifiers

PMID: 14656289
DOI: 10.1046/j.1460-9568.2003.03053.x

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