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Article

Endoplasmic reticulum stress initiates apoptotic death induced by STI571 inhibition of p210 bcr-abl tyrosine kinase.

Leukemia research - 1 Feb 2004

Pattacini Laura, Mancini Manuela, Mazzacurati Lucia, Brusa Gianluca, Benvenuti Michela, Martinelli Giovanni, Baccarani Michele, Santucci Maria Alessandra

Abstract excerpt

The endoplasmic reticulum (ER) is the site where proteins destined to either secretion or different subcellular compartments assemble and the major storage of intracellular Ca(2+). The ER stress resulting from a variety of toxic insults leads to apoptosis. Here, we showed that the apoptotic death...

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Identifiers

PMID: 14654084
DOI: 10.1016/s0145-2126(03)00218-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14654084-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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