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Article

There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum.

Biochimica et biophysica acta - 1 Mar 2004

Annis Matthew G, Yethon Jeremy A, Leber Brian, Andrews David W

Abstract excerpt

Proteins of the Bcl-2 family are important regulators of cell fate. The role of these proteins in controlling mitochondrial apoptotic processes has been extensively investigated, although exact molecular mechanisms are incompletely understood. However, mounting evidence indicates that these proteins also function at the endoplasmic reticulum and other locations within the cell. Both pro- and anti-apoptotic Bcl-2...

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Identifiers

PMID: 14996496
DOI: 10.1016/j.bbamcr.2003.07.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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