Article
The population genetics of alleles affecting enzyme activity.
Journal of theoretical biology - 7 Aug 1992
Hastings I M
Abstract excerpt
It is possible to predict the population genetics of allozymes by assuming that fitness is proportional to flux through a biochemical pathway. The model presented here extends previous work by incorporating two additional features of biological realism. Firstly, that more than one biochemical route may exist between any two metabolites. The major routes have been identified as the classical biochemical pathways...
Topics
- Animals
- Biological Evolution
- Drosophila
- Enzymes
- Models, Genetic
- Mutation
