Article
Identification of nine genomic regions of amplification in urothelial carcinoma, correlation with stage, and potential prognostic and therapeutic value.
PloS one - 1 Jan 2013
Chekaluk Yvonne, Wu Chin-Lee, Rosenberg Jonathan, Riester Markus, Dai Qishan, Lin Sharron, Guo Yanan, McDougal W Scott, Kwiatkowski David J
Abstract excerpt
We performed a genome wide analysis of 164 urothelial carcinoma samples and 27 bladder cancer cell lines to identify copy number changes associated with disease characteristics, and examined the association of amplification events with stage and grade of disease. Multiplex inversion probe (MIP) analysis, a recently developed genomic technique, was used to study 80 urothelial carcinomas to identify mutations and...
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