Article
mtDNA mutations in tumors of the central nervous system reflect the neutral evolution of mtDNA in populations.
Oncogene - 12 Feb 2004
Vega Ana, Salas Antonio, Gamborino Elena, Sobrido María Jesús, Macaulay Vincent, Carracedo Angel
Abstract excerpt
Mitochondrial DNA (mtDNA) instability has been observed in different types of cancer, including colorectal, breast, and gastric cancer. The relationship between the occurrence of such alteration and the nuclear microsatellite instability (nMI) status of the neoplastic cells remains controversial....
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