Article
A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease.
Gastroenterology - 1 Oct 2003
Mühlbauer Marcus, Bosserhoff Anja K, Hartmann Arndt, Thasler Wolfgang E, Weiss Thomas S, Herfarth Hans, Lock Guntram, Schölmerich Jürgen, Hellerbrand Claus
Abstract excerpt
BACKGROUND AND AIMS: Factors influencing the progression of chronic hepatitis C virus (HCV) infection are poorly understood. Monocyte chemotactic protein-1 (MCP-1) is a potent chemokine, and its hepatic expression is up-regulated during chronic HCV infection mainly in activated hepatic stellate c...
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