Article
Analysis of the rat connexin 43 proximal promoter in neonatal cardiomyocytes.
Gene - 11 Dec 2003
Teunissen Birgit E J, Jansen Anita T, van Amersfoorth Shirley C M, O'Brien Terrence X, Jongsma Habo J, Bierhuizen Marti F A
Abstract excerpt
Altered transcriptional control is likely to contribute to the down-regulation of connexin 43 (Cx43) expression observed in many forms of heart disease. However, little is known about the factors regulating Cx43 transcription in the heart under (patho)physiological conditions. Therefore, a systematic study of rat Cx43 (rCx43) proximal promoter regulation in rat primary neonatal ventricular cardiomyocytes (NCM)...
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