Article
Identification of two regulatory elements within the promoter region of the mouse connexin 43 gene.
The Journal of biological chemistry - 24 Feb 1995
Chen Z Q, Lefebvre D, Bai X H, Reaume A, Rossant J, Lye S J
Abstract excerpt
To define the minimal sequences required for expression of the connexin 43 gene (cx43) in myometrial cells, we generated 5' deletion constructs of a fragment extending 1686 base pairs upstream and 162 base pairs downstream of the transcription start site and determined their ability to drive expression of the chloramphenicol acetyltransferase reporter gene in transfected myometrial cell lines. Our investigation...
Topics
- Animals
- Base Sequence
- Chloramphenicol O-Acetyltransferase
- Connexin 43
- DNA Probes
- Female
- Mice
- Molecular Sequence Data
- Mutation
- Myometrium
- Nuclear Proteins