Article
Association of IL-10 (-819T/C, -592A/C and -1082A/G) and IL-6 -174G/C gene polymorphism and the risk of pneumonia-induced sepsis.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2017
Mao Zheng-Rong, Zhang Shao-Lei, Feng Bo
Abstract excerpt
CONTEXT: Association between inherited variants and the risks of sepsis is controversial. OBJECTIVE: To evaluate the risk of pneumonia-induced sepsis by examining its linkage with polymorphisms of IL-6 and IL-10. MATERIALS AND METHODS: Samples were obtained from 188 pneumonia-induced sepsis patients, 162 pneumonia patients and 200 healthy controls. RESULTS: Subjects with IL-10 -1082 AA genotypes and IL-6 -174 CC...
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