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Article

Variation in the hepatitis C virus NS5a region in relation to hypervariable region 1 heterogeneity during interferon treatment.

Journal of medical virology - 1 Sept 1998

Odeberg J, Yun Z, Sönnerborg A, Weiland O, Lundeberg J

Abstract excerpt

The putative interferon sensitivity determining region (ISDR) in the NS5a region of the hepatitis C virus (HCV) was analyzed in 13 interferon alpha (IFN-alpha) treated patients representing genotypes 1a, 1b, and 2b. These patients had previously been followed longitudinally during treatment with respect to viral load and to virus heterogeneity using the hypervariable region 1 (HVR1) sequence as a marker. In the...

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Source

Identifiers

PMID: 9700630
DOI: 10.1002/(sici)1096-9071(199809)56:1<33::aid-jmv6>3.0.co;2-o

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variation in the hepatitis C virus NS5a region in relation to hypervariable region 1 heterogeneity during interferon treatment.PMID 9700630Read ↗

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Mutations in different regions of the genome of hepatitis C virus genotype 1b and association with response to interferon therapy.Semantic proximity Read ↗

Hepatitis C virus E2 and NS5A region variability during sequential treatment with two interferon-alpha preparations.Semantic proximity Read ↗

Prospective characterization of full-length hepatitis C virus NS5A quasispecies during induction and combination antiviral therapy.Semantic proximity Read ↗

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Hepatitis C virus and the controversial role of the interferon sensitivity determining region in the response to interferon treatment.Semantic proximity Read ↗

The clinical significance of changes in genetic heterogeneity of the hypervariable region 1 in chronic hepatitis C with interferon therapy.Semantic proximity Read ↗

Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection.Semantic proximity Read ↗

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