Variation in the hepatitis C virus NS5a region in relation to hypervariable region 1 heterogeneity during interferon treatment.

doi:10.1002/(sici)1096-9071(199809)56:1<33::aid-jmv6>3.0.co;2-o

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Article

Variation in the hepatitis C virus NS5a region in relation to hypervariable region 1 heterogeneity during interferon treatment.

Journal of medical virology - 1 Sept 1998

Odeberg J, Yun Z, Sönnerborg A, Weiland O, Lundeberg J

Abstract excerpt

The putative interferon sensitivity determining region (ISDR) in the NS5a region of the hepatitis C virus (HCV) was analyzed in 13 interferon alpha (IFN-alpha) treated patients representing genotypes 1a, 1b, and 2b. These patients had previously been followed longitudinally during treatment with...

Topics

Amino Acid Sequence
Genetic Heterogeneity
Genetic Variation
Hepacivirus
Hepatitis C
Humans
Interferons
Molecular Sequence Data
Phylogeny
Viral Nonstructural Proteins

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