Intra- and interbacterial genetic exchange of Lyme disease spirochete erp genes generates sequence identity amidst diversity.

Abstract excerpt

All isolates of the spirochete Borrelia burgdorferi contain multiple, different plasmids of the cp32 family, each of which contains a locus encoding Erp surface proteins. Many of these proteins are known to bind host complement regulatory factor H, enabling the bacteria to avoid killing by the alternative complement pathway during vertebrate infection. In the present study, we characterized the erp loci and cp32...

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