Article
Borrelia burgdorferiEbfC, a Novel, Chromosomally Encoded Protein, Binds Specific DNA Sequences Adjacent toerpLoci on the Spirochete's Resident cp32 Prophages
1 Jun 2006
Abstract excerpt
All examined isolates of the Lyme disease spirochete, Borrelia burgdorferi, naturally maintain numerous variants of a prophage family as circular cp32 episomes. Each cp32 carries a locus encoding one or two different Erp outer membrane, surface-exposed lipoproteins. Many of the Erp proteins bind a host complement regulator, factor H, which is hypothesized to protect the spirochete from complement-mediated...
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