Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exogenous fibroblast growth factor-2 induces a transformed phenotype in vascular kaposi's sarcoma-like cells.

Molecular cell biology research communications : MCBRC - 1 Oct 2000

Cavallaro U, Soria M R, Montesano R

Abstract excerpt

Vascular TTB cells derive from murine Kaposi's sarcoma-like dermal lesions and share several phenotypic features with AIDS-associated KS spindle cells. We have recently reported that fibroblast growth factor-2 (FGF-2) promotes dramatic cytoskeletal and morphological alterations in TTB cells, concomitant with the induction of an autocrine loop for hepatocyte growth factor and a relocalization of the urokinase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autocrine Communication
Share to Fibroblast Growth Factor 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Products, tat

Share to Sarcoma, Kaposi

Share to Sepharose

Share to tat Gene Products, Human Immunodeficiency Virus

Share to Thrombospondin 1

Share to Tumor Stem Cell Assay

Source

Identifiers

PMID: 11409912
DOI: 10.1006/mcbr.2001.0278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exogenous fibroblast growth factor-2 induces a transformed phenotype in vascular kaposi's sarcoma-like cells.PMID 11409912Read ↗

Spindle cells isolated from Kaposi's sarcoma-like lesions of BKV/tat-transgenic mice co-express markers of different cell types.Semantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Tat Accelerates Kaposi Sarcoma-Associated Herpesvirus Kaposin A-Mediated Tumorigenesis of Transformed Fibroblasts In Vitro as well as in Nude and Immunocompetent MiceSemantic proximity Read ↗

gamma-Interferon produced by CD8+ T cells infiltrating Kaposi's sarcoma induces spindle cells with angiogenic phenotype and synergy with human immunodeficiency virus-1 Tat protein: an immune response to human herpesvirus-8 infection?Semantic proximity Read ↗

Expression of int-2 oncogene in Kaposi's sarcoma lesions.Semantic proximity Read ↗

Gene Regulation and Functional Alterations Induced by Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORFK13/vFLIP in Endothelial CellsSemantic proximity Read ↗

Establishment and characterization of two new Kaposi's sarcoma cell cultures from an AIDS and a non-AIDS patient.Semantic proximity Read ↗

Manipulation of endothelial cells by KSHV: implications for angiogenesis and aberrant vascular differentiation.Semantic proximity Read ↗

Activation of NF-kappaB by the latent vFLIP gene of Kaposi's sarcoma-associated herpesvirus is required for the spindle shape of virus-infected endothelial cells and contributes to their proinflammatory phenotype.Semantic proximity Read ↗

Alpha5 and alpha2 integrin gene transfers mimic the PDGF-B-induced transformed phenotype of fibroblasts in human skin.Semantic proximity Read ↗

Kaposi’s Sarcoma-Associated Herpesvirus Induction of Chromosome Instability in Primary Human Endothelial CellsSemantic proximity Read ↗

Long-term infection and transformation of dermal microvascular endothelial cells by human herpesvirus 8.Semantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.